GCG monoclonal antibody, clone AOAF-7
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GCG monoclonal antibody, clone AOAF-7 (Cat # MAB20093).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human GCG.
Immunogen
A synthetic peptide corresponding to human GCG.
Host
Rabbit
Theoretical MW (kDa)
20.909
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HepG2 cell lysate with GCG monoclonal antibody, clone AOAF-7 (Cat # MAB20093).Immunohistochemistry
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Gene Info — GCG
Entrez GeneID
2641Protein Accession#
P01275Gene Name
GCG
Gene Alias
GLP1, GLP2, GRPP
Gene Description
glucagon
Omim ID
138030Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq
Other Designations
glicentin-related polypeptide|glucagon-like peptide 1|glucagon-like peptide 2
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Interactome
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Pathway
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Disease
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