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Last updated: 2021/8/8

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GDNF monoclonal antibody, clone ABDB-7 

  • Catalog # : MAB20084
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human GDNF.
  • Immunogen:
  • A synthetic peptide corresponding to human GDNF.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 23.72
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of HepG2 cell lysate with GDNF monoclonal antibody, clone ABDB-7 (Cat # MAB20084).
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 2668
  • Gene Name:
  • GDNF
  • Gene Alias:
  • ATF1,ATF2,HFB1-GDNF
  • Gene Description:
  • glial cell derived neurotrophic factor
  • Gene Summary:
  • This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. In addition to the transcript encoding GDNF, two additional alternative transcripts encoding distinct proteins, referred to as astrocyte-derived trophic factors, have also been described. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq
  • Other Designations:
  • astrocyte-derived trophic factor,glial cell line derived neurotrophic factor,glial derived neurotrophic factor
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