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Last updated: 2021/8/8

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GCLC monoclonal antibody, clone ABBG-7 

  • Catalog # : MAB20082
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human GCLC.
  • Immunogen:
  • A synthetic peptide corresponding to human GCLC.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 72.766
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of HepG2 cell lysate with GCLC monoclonal antibody, clone ABBG-7 (Cat # MAB20082).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2729
  • Gene Name:
  • GCLC
  • Gene Alias:
  • GCS,GLCL,GLCLC
  • Gene Description:
  • glutamate-cysteine ligase, catalytic subunit
  • Gene Summary:
  • Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene encoding the catalytic subunit encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Deficiency of gamma-glutamylcysteine synthetase in human is associated with enzymopathic hemolytic anemia. [provided by RefSeq
  • Other Designations:
  • gamma-glutamylcysteine synthetase
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