FUS monoclonal antibody, clone IHC-6
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of K562 cell lysate with FUS monoclonal antibody, clone IHC-6 (Cat # MAB20064).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human FUS.
Immunogen
A synthetic peptide corresponding to human FUS.
Host
Rabbit
Theoretical MW (kDa)
53.426
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of K562 cell lysate with FUS monoclonal antibody, clone IHC-6 (Cat # MAB20064).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — FUS
Entrez GeneID
2521Protein Accession#
P35637Gene Name
FUS
Gene Alias
CHOP, FUS-CHOP, FUS1, TLS, TLS/CHOP, hnRNP-P2
Gene Description
fusion (involved in t(12;16) in malignant liposarcoma)
Omim ID
137070Gene Ontology
HyperlinkGene Summary
This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6. [provided by RefSeq
Other Designations
FUS-CHOP fusion protein|FUS-CHOP protein fusion|Fusion gene in myxoid liposarcoma|fus-like protein|fus/tls-chop oncogene|heterogeneous nuclear ribonucleoprotein P2|translocated in liposarcoma
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Interactome
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Disease
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