FOSB monoclonal antibody, clone DFO-6
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of C6 cell lysate with FOSB monoclonal antibody, clone DFO-6 (Cat # MAB20054).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of mouse brain with FOSB monoclonal antibody, clone DFO-6 (Cat # MAB20054).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human FOSB.
Immunogen
A synthetic peptide corresponding to human FOSB.
Host
Rabbit
Theoretical MW (kDa)
35.928
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Immunoprecipitation (1:20)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of C6 cell lysate with FOSB monoclonal antibody, clone DFO-6 (Cat # MAB20054).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of mouse brain with FOSB monoclonal antibody, clone DFO-6 (Cat # MAB20054).Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — FOSB
Entrez GeneID
2354Protein Accession#
P53539Gene Name
FOSB
Gene Alias
AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291
Gene Description
FBJ murine osteosarcoma viral oncogene homolog B
Omim ID
164772Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
activator protein 1|oncogene FOS-B
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Interactome
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Disease
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