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Last updated: 2022/5/22

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EDNRB monoclonal antibody, clone AABI-5 

  • Catalog # : MAB20010
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human EDNRB.
  • Immunogen:
  • A synthetic peptide corresponding to human EDNRB.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 49.644
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of 293T cell lysate with EDNRB monoclonal antibody, clone AABI-5 (Cat # MAB20010).
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1910
  • Gene Name:
  • EDNRB
  • Gene Alias:
  • ABCDS,ETB,ETBR,ETRB,HSCR,HSCR2
  • Gene Description:
  • endothelin receptor type B
  • Gene Summary:
  • The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally distinct. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000178736,endothelin receptor non-selective type
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