SLC9A3R1 monoclonal antibody, clone IIH-19
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HepG2 and Lane 2: PC12 cell lysates with SLC9A3R1 monoclonal antibody, clone IIH-19 (Cat # MAB20002).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SLC9A3R1.
Immunogen
A synthetic peptide corresponding to human SLC9A3R1.
Host
Rabbit
Theoretical MW (kDa)
38.868
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HepG2 and Lane 2: PC12 cell lysates with SLC9A3R1 monoclonal antibody, clone IIH-19 (Cat # MAB20002).Immunohistochemistry
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Gene Info — SLC9A3R1
Entrez GeneID
9368Protein Accession#
O14745Gene Name
SLC9A3R1
Gene Alias
EBP50, NHERF, NHERF1, NPHLOP2
Gene Description
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
Omim ID
604990Gene Ontology
HyperlinkGene Summary
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer
Other Designations
sodium/hydrogen exchanger regulatory factor 1|solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatory factor 1
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Interactome
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Disease
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