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Last updated: 2022/5/15

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DYNLL1 monoclonal antibody, clone EDA-4 

  • Catalog # : MAB19994
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human DYNLL1.
  • Immunogen:
  • A synthetic peptide corresponding to human DYNLL1.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 103.66
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunocytochemistry (1:50-1:200)
    Immunofluorescence (1:50-1:200)
    Immunohistochemistry (1:50-1:200)
    Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of HeLa cell lysate with DYNLL1 monoclonal antibody, clone EDA-4 (Cat # MAB19994).
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunocytochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 8655
  • Gene Name:
  • DYNLL1
  • Gene Alias:
  • DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,MGC126137,MGC126138,PIN,hdlc1
  • Gene Description:
  • dynein, light chain, LC8-type 1
  • Gene Summary:
  • Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
  • Other Designations:
  • 8 kDa dynein light chain,cytoplasmic dynein light polypeptide,dynein light chain 1,dynein, cytoplasmic, light polypeptide 1,protein inhibitor of neuronal nitric oxide synthase
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