RNASEN monoclonal antibody, clone ABEF-4
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More Files
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Specifications
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human RNASEN.
Immunogen
A synthetic peptide corresponding to human RNASEN.
Host
Rabbit
Theoretical MW (kDa)
159.316
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Flow Cytometry (1:50)
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:1000-1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of 293 cell lysate with RNASEN monoclonal antibody, clone ABEF-4 (Cat # MAB19990).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Flow Cytometry
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Gene Info — RNASEN
Entrez GeneID
29102Protein Accession#
Q9NRR4Gene Name
RNASEN
Gene Alias
DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L
Gene Description
ribonuclease type III, nuclear
Omim ID
608828Gene Ontology
HyperlinkGene Summary
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM
Other Designations
drosha, double-stranded RNA-specific endoribonuclease|drosha, ribonuclease type III|nuclear RNase III Drosha|putative protein p241 which interacts with transcription factor Sp1|putative ribonuclease III|ribonuclease III, nuclear
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Interactomes
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Diseases
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