DBN1 monoclonal antibody, clone ABDC-4
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human DBN1.
Immunogen
A synthetic peptide corresponding to human DBN1.
Host
Rabbit
Theoretical MW (kDa)
71.429
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunoprecipitation (1:50)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of Lane 1: HeLa and Lane 2: PC-12 cell lysates with DBN1 monoclonal antibody, clone ABDC-4 (Cat # MAB19989).Immunocytochemistry
Immunofluorescence
Immunoprecipitation
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Gene Info — DBN1
Entrez GeneID
1627Protein Accession#
Q16643Gene Name
DBN1
Gene Alias
D0S117E, DKFZp434D064
Gene Description
drebrin 1
Omim ID
126660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq
Other Designations
drebrin E|drebrin E2|drebrin-1
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