CYBB monoclonal antibody, clone GOH-3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of MCF-7 cell lysate with CYBB monoclonal antibody.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CYBB.
Immunogen
A synthetic peptide corresponding to human CYBB.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MCF-7 cell lysate with CYBB monoclonal antibody. -
Gene Info — CYBB
Entrez GeneID
1536Protein Accession#
P04839Gene Name
CYBB
Gene Alias
CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX
Gene Description
cytochrome b-245, beta polypeptide
Gene Ontology
HyperlinkGene Summary
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq
Other Designations
OTTHUMP00000031915|cytochrome b-245 beta polypeptide
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Interactome
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Pathway
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Disease
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