CUBN monoclonal antibody, clone GA-3
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human CUBN.
Immunogen
A synthetic peptide corresponding to human CUBN.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human fetal kidney lysate with CUBN monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin-embedded human kidney with CUBN monoclonal antibody. -
Gene Info — CUBN
Entrez GeneID
8029Protein Accession#
O60494Gene Name
CUBN
Gene Alias
FLJ90055, FLJ90747, IFCR, MGA1, gp280
Gene Description
cubilin (intrinsic factor-cobalamin receptor)
Gene Ontology
HyperlinkGene Summary
Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq
Other Designations
OTTHUMP00000019220|cubilin|intrinsic factor B12-receptor|intrinsic factor-cobalamin receptor|intrinsic factor-vitamin B12 receptor
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Interactome
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Disease
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