SELP monoclonal antibody, clone AAEC-19
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More Files
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SELP.
Immunogen
A synthetic peptide corresponding to human SELP.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of HUVEC cell lysate with SELP monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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Gene Info — SELP
Entrez GeneID
6403Protein Accession#
P16109Gene Name
SELP
Gene Alias
CD62, CD62P, FLJ45155, GMP140, GRMP, LECAM3, PADGEM, PSEL
Gene Description
selectin P (granule membrane protein 140kDa, antigen CD62)
Gene Ontology
HyperlinkGene Summary
This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
Other Designations
OTTHUMP00000032609|antigen CD62|granulocyte membrane protein|leukocyte-endothelial cell adhesion molecule 3|platelet alpha-granule membrane protein|selectin P|selectin P (granule membrane protein 140kD, antigen CD62)
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Interactome
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Pathway
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Disease
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