PTGER3 monoclonal antibody, clone 5F5
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant PTGER3.
Immunogen
Recombinant protein of human PTGER3.
Host
Mouse
Reactivity
Bovine, Human, Rat
Form
Liquid
Isotype
IgG
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Recommend Usage
Western blot (1 to 5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis using PTGER3 monoclonal antibody, clone 5F5 (Cat # MAB1978) on porcine brain lysate at 1 ug/mL . -
Gene Info — PTGER3
Entrez GeneID
5733Gene Name
PTGER3
Gene Alias
EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302
Gene Description
prostaglandin E receptor 3 (subtype EP3)
Omim ID
176806Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011033|OTTHUMP00000011034|OTTHUMP00000011035|PGE receptor, EP3 subtype|prostaglandin E receotor EP3 subtype 3 isoform|prostaglandin E receptor 3, subtype EP3|prostaglandin E2 receptor|prostaglandin receptor (PGE-2)|prostanoid EP3 receptor
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Interactome
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Disease
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Publication Reference
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Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups: a double immunofluorescence study in the rat brain.
Nakamura K, Li YQ, Kaneko T, Katoh H, Negishi M.
Neuroscience 2001 Mar; 103(3):763.
Application:IF, Rat, Brain.
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Immunolocalization of the four prostaglandin E2 receptor proteins EP1, EP2, EP3, and EP4 in human kidney.
Morath R, Klein T, Seyberth HW, Nüsing RM.
Journal of the American Society of Nephrology 1999 Sep; 10(9):1851.
Application:IHC-Fr, WB-Ti, Human, Human kidneys.
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Immunocytochemical localization of prostaglandin EP3 receptor in the rat hypothalamus.
Nakamura K, Kaneko T, Yamashita Y, Hasegawa H, Katoh H, Ichikawa A, Negishi M.
Neuroscience Letters 1999 Jan; 260(2):117.
Application:IHC, WB-Ti, WB-Tr, Monkey, Rat, Brain, Kidney, COS-7 cells.
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Prostaglandin EP3 receptor protein in serotonin and catecholamine cell groups: a double immunofluorescence study in the rat brain.
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