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CASP10 monoclonal antibody, clone ICH-3 

  • Catalog # : MAB19696
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CASP10.
  • Immunogen:
  • A synthetic peptide corresponding to human CASP10.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 58.951
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Flow Cytometry (1:50)
    Immunohistochemistry (1:50-1:100)
    Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Jurkat cell lysate with CASP10 monoclonal antibody, clone ICH-3 (Cat # MAB19696).
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 843
  • Gene Name:
  • CASP10
  • Gene Alias:
  • ALPS2,FLICE2,MCH4
  • Gene Description:
  • caspase 10, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • FADD-like ICE2,Fas-associated death domain protein,ICE-like apoptotic protease 4,apoptotic protease MCH-4,caspase 10,caspase 10, apoptosis-related cysteine protease,interleukin-1B-converting enzyme 2
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  • Interactome
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