TP53BP2 monoclonal antibody, clone AOEA-20
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human TP53BP2.
Immunogen
A synthetic peptide corresponding to human TP53BP2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:200)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of MCF7 cell lysate with TP53BP2 monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Immunofluorescence
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Gene Info — TP53BP2
Entrez GeneID
7159Protein Accession#
Q13625Gene Name
TP53BP2
Gene Alias
53BP2, ASPP2, BBP, PPP1R13A, p53BP2
Gene Description
tumor protein p53 binding protein, 2
Omim ID
602143Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
BCL2-binding protein|NY-REN-51 antigen|apoptosis-stimulating protein of p53, 2|tumor suppressor p53-binding protein 2
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Interactome
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Disease
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