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CYP19A1 monoclonal antibody, clone AABB-3  

  • Catalog # : MAB19577
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic peptide of human CYP19A1.
  • Immunogen:
  • A synthetic peptide corresponding to human CYP19A1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunoprecipitation (1:50)
    Western Blot (1:500-1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage Instruction:
  • Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of rat brain lysate with CYP19A1 monoclonal antibody.
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 1588
  • Gene Name:
  • CYP19A1
  • Gene Alias:
  • ARO,ARO1,CPV1,CYAR,CYP19,MGC104309,P-450AROM
  • Gene Description:
  • cytochrome P450, family 19, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. The gene expresses two transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162543,aromatase,cytochrome P450, family 19,cytochrome P450, subfamily XIX (aromatization of androgens),estrogen synthetase,flavoprotein-linked monooxygenase,microsomal monooxygenase
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