AP2M1 monoclonal antibody, clone GDD-1
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of (1) HEK293 cell lysate; (2) MCF-7 cell lysate with AP2M1 monoclonal antibody.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human AP2M1.
Immunogen
A synthetic peptide corresponding to human AP2M1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:1000-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of (1) HEK293 cell lysate; (2) MCF-7 cell lysate with AP2M1 monoclonal antibody. -
Gene Info — AP2M1
Entrez GeneID
1173Protein Accession#
Q96CW1Gene Name
AP2M1
Gene Alias
AP50, CLAPM1, mu2
Gene Description
adaptor-related protein complex 2, mu 1 subunit
Omim ID
601024Gene Ontology
HyperlinkGene Summary
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AP-2 mu 2 chain|HA2 50 kDA subunit|clathrin adaptor complex AP2, mu subunit|clathrin assembly protein complex 2 medium chain|clathrin coat adaptor protein AP50|clathrin-associated/assembly/adaptor protein, medium 1|plasma membrane adaptor AP-2 50kDA prote
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Interactome
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Pathway
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Disease
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