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Last updated: 2016/12/4
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MITF monoclonal antibody, clone C5

  • Catalog # : MAB1955
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant MITF.
  • Immunogen:
  • Recombinant protein corresponding to N-terminus of human MITF.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Western blot (1 ug/mL)
    Immunoprecipitation (2 ug/mg of protein lysate)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining usin MITF monoclonal antibody, clone C5 (Cat # MAB1955) on formalin fixed, paraffin embedded human melanoma.
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gel Supershift Assay
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Gel Supershift Assay
  • Gene Information
  • Entrez GeneID:
  • 4286
  • Gene Name:
  • MITF
  • Gene Alias:
  • MI,WS2A,bHLHe32
  • Gene Description:
  • microphthalmia-associated transcription factor
  • Gene Summary:
  • This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000195123,OTTHUMP00000195140,homolog of mouse microphthalmia
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