SGCA monoclonal antibody, clone ABGE-19
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of human skeletal muscle lysate with SGCA monoclonal antibody.
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic peptide of human SGCA.
Immunogen
A synthetic peptide corresponding to human SGCA.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunohistochemistry (1:100-1:500)
Immunoprecipitation (1:40)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human skeletal muscle lysate with SGCA monoclonal antibody.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoprecipitation
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Gene Info — SGCA
Entrez GeneID
6442Protein Accession#
Q16586Gene Name
SGCA
Gene Alias
50-DAG, A2, ADL, DAG2, DMDA2, LGMD2D, SCARMD1, adhalin
Gene Description
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
50kD DAG|sarcoglycan, alpha
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Interactome
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Pathway
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