Mouse monoclonal antibody raised against native MVP.
Native purified human MVP.
Quality Control Testing:
Antibody Reactive Against Native Purified Protein.
Western blot (1 ug/mL) Immunoprecipitation (2 ug/mg of protein lysate) Immunohistochemistry on frozen and formalin to fixed/paraffin to embedded tissues (2 to 4 ug/mL) The optimal working dilution should be determined by the end
In PBS (0.08% sodium azide)
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq