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Last updated: 2020/11/22

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SPTBN4 monoclonal antibody, clone S393-2 (ATTO 655) 

  • Catalog # : MAB19437
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant human SPTBN4.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 1621-1832 at C-terminus repeats 14 to 15 of human Beta4-spectrin.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody detects ~>200kDa. Does not cross react with other Beta-spectrins.
  • Form:
  • Liquid
  • Conjugation:
  • ATTO 655
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Immunocytochemistry
    Immunofluorescence
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western Blot analysis of COS-Beta-4-Spectrin-His.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of SK-N-BE cell line (A) DAPI (blue) nuclear stain, (B) Phalloidin Texas Red F-Actin stain, (C) SPTBN4 Antibody and (D) Composite.
  • Immunofluorescence
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunofluorescence
  • Gene Information
  • Gene Name:
  • SPTBN4
  • Gene Alias:
  • KIAA1642,QV,SPNB4,SPTBN3
  • Gene Description:
  • spectrin, beta, non-erythrocytic 4
  • Gene Summary:
  • Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • betaIV spectrin
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