STAT6 (phospho Y641) monoclonal antibody, clone G12
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of Daudi cell lysate with STAT6 (phospho Y641) monoclonal antibody, clone G12 (Cat # MAB19150). Lane 1: untreated or Lane 2: treated with IL-4.
Flow Cytometry
Flow cytometric analysis of U937 cells with STAT6 (phospho Y641) monoclonal antibody, clone G12 (Cat # MAB19150). Secondary antibody only negative control (blue) or untreated (red) or treated with IFNa and IL-4 (green).
-
Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human STAT6.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y641 of human STAT6.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western Blot analysis of Daudi cell lysate with STAT6 (phospho Y641) monoclonal antibody, clone G12 (Cat # MAB19150). Lane 1: untreated or Lane 2: treated with IL-4.Flow Cytometry
Flow cytometric analysis of U937 cells with STAT6 (phospho Y641) monoclonal antibody, clone G12 (Cat # MAB19150). Secondary antibody only negative control (blue) or untreated (red) or treated with IFNa and IL-4 (green). -
Gene Info — STAT6
Entrez GeneID
6778Gene Name
STAT6
Gene Alias
D12S1644, IL-4-STAT, STAT6B, STAT6C
Gene Description
signal transducer and activator of transcription 6, interleukin-4 induced
Omim ID
601512Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. [provided by RefSeq
Other Designations
STAT, interleukin4-induced|signal transducer and activator of transcription 6|transcription factor IL-4 STAT
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com