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Last updated: 2020/11/22

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STAT1 (phospho S727) monoclonal antibody, clone C6 

  • Catalog # : MAB19106
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human STAT1.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding Ser727 of human phospho STAT1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1k
  • Recommend Usage:
  • Flow Cytometry (1 ug/mL-0.001 ug/mL )
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 0.1% BSA, 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of U937 cell extract (1) treated with IL-4, (2) untreated with IL-4.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of U937 cells secondary antibody only negative control (blue) or untreated (red) or treated with IFNΑ IL4 and pervanadate (green) using STAT1 (phospho S727) monoclonal antibody.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6772
  • Gene Name:
  • STAT1
  • Gene Alias:
  • DKFZp686B04100,ISGF-3,STAT91
  • Gene Description:
  • signal transducer and activator of transcription 1, 91kDa
  • Gene Summary:
  • The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000165047,signal transducer and activator of transcription 1,signal transducer and activator of transcription-1,transcription factor ISGF-3 components p91/p84
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