SRC (phospho Y416) monoclonal antibody, clone C4 (SureLight 488)
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More Files
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Flow Cytometry
Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNΑ IL4 and pervanadate (green) using SRC (phospho Y416) monoclonal antibody (SureLight 488).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human SRC.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Tyr416 of human phospho SRC.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
SureLight 488
Purification
Protein A/G purification
Isotype
IgG1k
Recommend Usage
Flow Cytometry (5 uL/106 cells or 5 u per 100 uL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells unstained untreated cells as negative control (blue) or stained untreated (red) or treated with IFNΑ IL4 and pervanadate (green) using SRC (phospho Y416) monoclonal antibody (SureLight 488). -
Gene Info — SRC
Entrez GeneID
6714Protein Accession#
P12931Gene Name
SRC
Gene Alias
ASV, SRC1, c-SRC, p60-Src
Gene Description
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Omim ID
190090Gene Ontology
HyperlinkGene Summary
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000174476|OTTHUMP00000174477|proto-oncogene tyrosine-protein kinase SRC|protooncogene SRC, Rous sarcoma|tyrosine kinase pp60c-src|tyrosine-protein kinase SRC-1
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Interactome
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Pathway
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Disease
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