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Last updated: 2020/11/29

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RPS6 (phospho S235/S236) monoclonal antibody, clone R3A2 (APC) 

  • Catalog # : MAB19054
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human RPS6.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding S235/S236 of human RPS6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • APC
  • Purification:
  • Protein A/G Purification
  • Isotype:
  • IgG1k
  • Recommend Usage:
  • Flow Cytometry (5 uL/106 cells or 0.05 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 2-8°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of U937 cells unstained U0126 and SB20350 cells (blue) or stained and treated with U0126 plus SB20350 (red) or treated with TPA plus calyculin A (green) using RPS6 (phospho S235/S236) monoclonal antibody (APC).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 6194
  • Gene Name:
  • RPS6
  • Gene Alias:
  • -
  • Gene Description:
  • ribosomal protein S6
  • Gene Summary:
  • Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq
  • Other Designations:
  • 40S ribosomal protein S6,OTTHUMP00000021120,phosphoprotein NP33
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