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Last updated: 2020/11/22
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LCK (phospho Y505) monoclonal antibody, clone A3 

  • Catalog # : MAB18923
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human LCK.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding Y505 of human LCK.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of Jurkat cell lysate with LCK (phospho Y505) monoclonal antibody, clone A3 (Cat # MAB18923). Lane 1: treated or Lane 2: untreated with 200 nM calyculin A for 30min.
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of Daudi cells with LCK (phospho Y505) monoclonal antibody, clone A3 (Cat # MAB18923). Secondary antibody only negative control (blue) or untreated (red) or treated with IFNa + IL-4 + pervanadate (green).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 3932
  • Gene Name:
  • LCK
  • Gene Alias:
  • YT16,p56lck,pp58lck
  • Gene Description:
  • lymphocyte-specific protein tyrosine kinase
  • Gene Summary:
  • This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq
  • Other Designations:
  • T-lymphocyte specific protein tyrosine kinase p56lck,p56(LSTRA) protein-tyrosine kinase,protein tyrosine kinase,proto-oncogene tyrosine-protein kinase LCK
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