H2AFX (phospho S139) monoclonal antibody, clone 10000
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HEK293T cell lysate with H2AFX (phospho S139) monoclonal antibody, clone 10000 (Cat # MAB18900). Lane 1: treated or Lane 2: untreated with UV.
Flow Cytometry
Flow cytometric analysis of 293T cells with H2AFX (phospho S139) monoclonal antibody, clone 10000 (Cat # MAB18900). Secondary antibody only negative control (blue) or untreated (red) or treated with UV and PMA (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human H2AFX.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S139 of human H2AFX.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry
Western Blot
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
Storage Instruction
Store at -20°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HEK293T cell lysate with H2AFX (phospho S139) monoclonal antibody, clone 10000 (Cat # MAB18900). Lane 1: treated or Lane 2: untreated with UV.Flow Cytometry
Flow cytometric analysis of 293T cells with H2AFX (phospho S139) monoclonal antibody, clone 10000 (Cat # MAB18900). Secondary antibody only negative control (blue) or untreated (red) or treated with UV and PMA (green). -
Gene Info — H2AFX
Entrez GeneID
3014Gene Name
H2AFX
Gene Alias
H2A.X, H2A/X, H2AX
Gene Description
H2A histone family, member X
Omim ID
601772Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq
Other Designations
H2AX histone
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Interactome
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Pathway
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Disease
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