H2AFX (phospho S139) monoclonal antibody, clone 1B3 (PE)
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More Files
- More Functions
Flow Cytometry
Flow cytometric analysis of 293T cells with H2AFX (phospho S139) monoclonal antibody, clone 1B3 (PE) (Cat # MAB18898). Unstained cells (blue) or stained untreated (red) or treated with UV and TPA (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human H2AFX.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding S139 of human H2AFX.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
PE
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of 293T cells with H2AFX (phospho S139) monoclonal antibody, clone 1B3 (PE) (Cat # MAB18898). Unstained cells (blue) or stained untreated (red) or treated with UV and TPA (green). -
Gene Info — H2AFX
Entrez GeneID
3014Gene Name
H2AFX
Gene Alias
H2A.X, H2A/X, H2AX
Gene Description
H2A histone family, member X
Omim ID
601772Gene Ontology
HyperlinkGene Summary
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq
Other Designations
H2AX histone
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Interactome
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Pathway
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Disease
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