BTK (phospho Y551) monoclonal antibody, clone G12 (APC)
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More Files
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Flow Cytometry
Flow cytometric analysis of Ramos cells with BTK (phospho Y551) monoclonal antibody, clone G12 (APC) (Cat # MAB18832). Unstained untreated as negative control (blue) or stained untreated (red) or treated with pervanadate (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human BTK.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y551 of human BTK.
Host
Rabbit
Reactivity
Human
Form
Liquid
Conjugation
APC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of Ramos cells with BTK (phospho Y551) monoclonal antibody, clone G12 (APC) (Cat # MAB18832). Unstained untreated as negative control (blue) or stained untreated (red) or treated with pervanadate (green). -
Gene Info — BTK
Entrez GeneID
695Gene Name
BTK
Gene Alias
AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA
Gene Description
Bruton agammaglobulinemia tyrosine kinase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
Other Designations
B-cell progenitor kinase|Bruton tyrosine kinase|OTTHUMP00000023676|OTTHUMP00000063593|agammaglobulinemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK
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Interactome
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Pathway
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Disease
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