BTK (phospho Y223) monoclonal antibody, clone B4 (FITC)
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More Files
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Flow Cytometry
Flow cytometric analysis of U937 cells with BTK (phospho Y223) monoclonal antibody, clone B4 (FITC) (Cat # MAB18824). Unstained cells negative control (blue) or untreated (red) or treated with IFNa IL4 and PV (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human BTK.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding Y223 of human BTK.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
FITC
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of U937 cells with BTK (phospho Y223) monoclonal antibody, clone B4 (FITC) (Cat # MAB18824). Unstained cells negative control (blue) or untreated (red) or treated with IFNa IL4 and PV (green). -
Gene Info — BTK
Entrez GeneID
695Gene Name
BTK
Gene Alias
AGMX1, AT, ATK, BPK, IMD1, MGC126261, MGC126262, PSCTK1, XLA
Gene Description
Bruton agammaglobulinemia tyrosine kinase
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq
Other Designations
B-cell progenitor kinase|Bruton tyrosine kinase|OTTHUMP00000023676|OTTHUMP00000063593|agammaglobulinemia tyrosine kinase|dominant-negative kinase-deficient Brutons tyrosine kinase|tyrosine-protein kinase BTK
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Interactome
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Pathway
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Disease
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