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Last updated: 2020/11/29
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BLNK (phospho Y84) monoclonal antibody, clone H4 (PE) 

  • Catalog # : MAB18817
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human BLNK.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding Y84 of human BLNK.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry (5 uL/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of Daudi cells with BLNK (phospho Y84) monoclonal antibody, clone H4 (PE) (Cat # MAB18817). Untreated cells as negative control (blue) or stained untreated (red) or treated with IFNa + IL-4 + pervanadate (green).
  • Application Image
  • Gene Information
  • Gene Name:
  • BLNK
  • Gene Alias:
  • BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65
  • Gene Description:
  • B-cell linker
  • Gene Summary:
  • This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • B cell linker protein,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,OTTHUMP00000020167,Src homology 2 domain-containing leukocyte protein of 65 kDa
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