ATF2 (phospho T71) monoclonal antibody, clone G3 (PE)
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More Files
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Flow Cytometry
Flow cytometric analysis of Jurkat cells with ATF2 (phospho T71) monoclonal antibody, clone G3 (PE) (Cat # MAB18804). Secondary antibody only negative control (blue) or untreated (red) or treated with anisomycin (green).
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Specification
Product Description
Rabbit monoclonal antibody raised against synthetic phosphopeptide of human ATF2.
Immunogen
A synthetic phosphopeptide corresponding to residues surrounding T71 of human ATF2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Conjugation
PE
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (5 uL/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.2% BSA, 0.09% sodium azide).
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
Flow cytometric analysis of Jurkat cells with ATF2 (phospho T71) monoclonal antibody, clone G3 (PE) (Cat # MAB18804). Secondary antibody only negative control (blue) or untreated (red) or treated with anisomycin (green). -
Gene Info — ATF2
Entrez GeneID
1386Gene Name
ATF2
Gene Alias
CRE-BP1, CREB2, HB16, MGC111558, TREB7
Gene Description
activating transcription factor 2
Omim ID
123811Gene Ontology
HyperlinkGene Summary
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000163262|activating transcription factor 2 splice variant ATF2-var2|cAMP responsive element binding protein 2, formerly
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Interactome
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Pathway
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Disease
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