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Last updated: 2016/10/23
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ESR1 monoclonal antibody, clone TE111.5D11

  • Catalog # : MAB1880
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant ESR1.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 302-595 of human ESR1.
  • Host:
  • Mouse
  • Reactivity:
  • Bovine, Hamster, Human, Mouse, Rabbit, Rat
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunoprecipitation (2 ug/mg)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis using ESR1 monoclonal antibody, clone TE111.5D11 (Cat # MAB1880) on human MCF-7 cells at 1-2 ug/mL .
  • Immunoprecipitation
  • Gel Supershift Assay
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunoprecipitation
  • Gel Supershift Assay
  • Gene Information
  • Entrez GeneID:
  • 2099
  • Gene Name:
  • ESR1
  • Gene Alias:
  • DKFZp686N23123,ER,ESR,ESRA,Era,NR3A1
  • Gene Description:
  • estrogen receptor 1
  • Gene Summary:
  • This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017718,OTTHUMP00000017719,estrogen receptor alpha
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