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Last updated: 2020/11/22
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EIF4EBP1 (phospho T37/T46) monoclonal antibody, clone A5 

  • Catalog # : MAB18765
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against synthetic phosphopeptide of human EIF4EBP1.
  • Immunogen:
  • A synthetic phosphopeptide corresponding to residues surrounding T37/T46 of human EIF4EBP1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Purification:
  • Protein A/G purification
  • Isotype:
  • IgG1, kappa
  • Recommend Usage:
  • Flow Cytometry
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Western Blot
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.1% BSA and 0.02% sodium azide).
  • Storage Instruction:
  • Store at -20°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western Blot analysis of K562 cell lysate with EIF4EBP1 (phospho T37/T46) monoclonal antibody, clone A5 (Cat # MAB18765). Lane 1: untreated or Lane 2: treated with imatinib.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Flow Cytometry
  • Flow Cytometry
  • Flow cytometric analysis of C6 cells with EIF4EBP1 (phospho T37/T46) monoclonal antibody, clone A5 (Cat # MAB18765). Untreated cells stained with secondary antibody as negative control (blue) or untreated (red) or treated with UV and TPA (green).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 1978
  • Gene Name:
  • EIF4EBP1
  • Gene Alias:
  • 4E-BP1,4EBP1,BP-1,MGC4316,PHAS-I
  • Gene Description:
  • eukaryotic translation initiation factor 4E binding protein 1
  • Gene Summary:
  • This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq
  • Other Designations:
  • eIF4E-binding protein 1,phosphorylated heat- and acid-stable protein regulated by insulin 1
  • Interactome
  • Interactome
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