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Last updated: 2016/12/4
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CYP3A5 monoclonal antibody, clone F18 P3 B6

  • Catalog # : MAB1859
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of CYP3A5.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human CYP3A5.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Quality Control Testing:
  • Antibody Reactive Against Synthetic Peptide.
  • Recommend Usage:
  • Western Blot (1-2 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.08% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using CYP3A5 monoclonal antibody, clone F18 P3 B6 (Cat # MAB1859) on recombinant CYP3A5 proteins.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1577
  • Gene Name:
  • CYP3A5
  • Gene Alias:
  • CP35,P450PCN3,PCN3
  • Gene Description:
  • cytochrome P450, family 3, subfamily A, polypeptide 5
  • Gene Summary:
  • This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. [provided by RefSeq
  • Other Designations:
  • aryl hydrocarbon hydroxylase,cytochrome P-450,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5,flavoprotein-linked monooxygenase,microsomal monooxygenase,niphedipine oxidase,xenobiotic monooxygenase
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