AFP monoclonal antibody, clone C3
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of AFP expression in HepG2 cell lysate (10 ug/lane) with AFP monoclonal antibody, clone C3 (Cat # MAB1822) at 4 ug/mL .
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Specification
Product Description
Mouse monoclonal antibody raised against AFP.
Immunogen
Human AFP.
Host
Mouse
Reactivity
Dog, Human, Pig
Form
Liquid
Isotype
IgG2a
Quality Control Testing
Antibody Reactive Against AFP.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.08% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of AFP expression in HepG2 cell lysate (10 ug/lane) with AFP monoclonal antibody, clone C3 (Cat # MAB1822) at 4 ug/mL .Immunohistochemistry
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Gene Info — AFP
Entrez GeneID
174Gene Name
AFP
Gene Alias
FETA, HPAFP
Gene Description
alpha-fetoprotein
Omim ID
104150Gene Ontology
HyperlinkGene Summary
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq
Other Designations
OTTHUMP00000160480|alpha-1-fetoprotein|alpha-fetoglobulin
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Interactome
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Disease
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Publication Reference
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Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.
Sato Y, Araki H, Kato J, Nakamura K, Kawano Y, Kobune M, Sato T, Miyanishi K, Takayama T, Takahashi M, Takimoto R, Iyama S, Matsunaga T, Ohtani S, Matsuura A, Hamada H, Niitsu Y.
Blood 2005 Jul; 106(2):756.
Application：IF, IHC, Human, Rat, Liver, hMSCs.
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Human alpha-fetoprotein epitopes as revealed by monoclonal antibodies.
Yazova AK, Goussev AI, Poltoranina VS, Yakimenko EF.
Immunology Letters 1990 Sep; 25(4):325.
Application：ELISA, Human, Recombinant proteins.
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Human mesenchymal stem cells xenografted directly to rat liver are differentiated into human hepatocytes without fusion.
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