CD1B monoclonal antibody, clone 5G3D4
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD1B-hIgGFc transfected HEK293 cell lysates with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000).
Flow Cytometry
Flow cytometric analysis of Raji cells with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CD1B.
Immunogen
Recombinant protein corresponding to amino acids 18-303 of human CD1B.
Host
Mouse
Theoretical MW (kDa)
37
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD1B-hIgGFc transfected HEK293 cell lysates with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000).Flow Cytometry
Flow cytometric analysis of Raji cells with CD1B monoclonal antibody, clone 5G3D4 (Cat # MAB18000) (Green). Red: Negative Control. -
Gene Info — CD1B
Entrez GeneID
910Protein Accession#
P29016Gene Name
CD1B
Gene Alias
CD1, CD1A, MGC125990, MGC125991, R1
Gene Description
CD1b molecule
Omim ID
188360Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq
Other Designations
CD1B antigen|CD1B antigen, b polypeptide|OTTHUMP00000018908|T-cell surface glycoprotein CD1b|cortical thymocyte antigen CD1B|differentiation antigen CD1-alpha-3
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Interactome
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Pathway
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Disease
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