KLRB1 monoclonal antibody, clone 4C6A11
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human KLRB1.
Immunogen
Recombinant protein corresponding to amino acids 67-225 of human KLRB1.
Host
Mouse
Theoretical MW (kDa)
25.4
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: KLRB1-hIgGFc transfected HEK293 cell lysates with KLRB1 monoclonal antibody, clone 4C6A11 (Cat # MAB17997).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with KLRB1 monoclonal antibody, clone 4C6A11 (Cat # MAB17997).Flow Cytometry
Flow cytometric analysis of Raji cells with KLRB1 monoclonal antibody, clone 4C6A11 (Cat # MAB17997) (Green). Red: Negative Control. -
Gene Info — KLRB1
Entrez GeneID
3820Protein Accession#
Q12918Gene Name
KLRB1
Gene Alias
CD161, CLEC5B, MGC138614, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Gene Description
killer cell lectin-like receptor subfamily B, member 1
Omim ID
602890Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq
Other Designations
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Interactome
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Disease
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