TNFRSF13C monoclonal antibody, clone 5A9B10
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TNFRSF13C-hIgGFc transfected HEK293 cell lysates with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995).
Flow Cytometry
Flow cytometric analysis of Raji cells with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human TNFRSF13C.
Immunogen
Recombinant protein corresponding to amino acids 1-78 of human TNFRSF13C.
Host
Mouse
Theoretical MW (kDa)
18.9
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: TNFRSF13C-hIgGFc transfected HEK293 cell lysates with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995).Flow Cytometry
Flow cytometric analysis of Raji cells with TNFRSF13C monoclonal antibody, clone 5A9B10 (Cat # MAB17995) (Green). Red: Negative Control. -
Gene Info — TNFRSF13C
Entrez GeneID
115650Protein Accession#
Q96RJ3Gene Name
TNFRSF13C
Gene Alias
BAFF-R, BAFFR, CD268, MGC138235
Gene Description
tumor necrosis factor receptor superfamily, member 13C
Omim ID
606269Gene Ontology
HyperlinkGene Summary
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq
Other Designations
B cell-activating factor receptor|BAFF receptor|OTTHUMP00000028746
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Pathway
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Disease
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