CD1C monoclonal antibody, clone 3G1B3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD1C-hIgGFc transfected HEK293 cell lysates with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded rectum cancer tissues with DAB staining.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991).
Flow Cytometry
Flow cytometric analysis of Ramos cells with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CD1C.
Immunogen
Recombinant protein corresponding to amino acids 18-302 of human CD1C.
Host
Mouse
Theoretical MW (kDa)
37.7
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:1000)
Western Blot (1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CD1C-hIgGFc transfected HEK293 cell lysates with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded rectum cancer tissues with DAB staining.Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991).Flow Cytometry
Flow cytometric analysis of Ramos cells with CD1C monoclonal antibody, clone 3G1B3 (Cat # MAB17991) (Green). Red: Negative Control. -
Gene Info — CD1C
Entrez GeneID
911Protein Accession#
P29017Gene Name
CD1C
Gene Alias
BDCA1, CD1, CD1A, R7
Gene Description
CD1c molecule
Omim ID
188340Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq
Other Designations
CD1C antigen|CD1C antigen, c polypeptide|OTTHUMP00000018909|T-cell surface glycoprotein CD1c|cortical thymocyte antigen CD1C|differentiation antigen CD1-alpha-3
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Pathway
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Disease
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