PVRL2 monoclonal antibody, clone 4A11B12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PVRL2-hIgGFc transfected HEK293 cell lysates with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975).
Flow Cytometry
Flow cytometric analysis of Ramos cells with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PVRL2.
Immunogen
Recombinant protein corresponding to amino acids 58-212 of human PVRL2.
Host
Mouse
Theoretical MW (kDa)
57.7
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PVRL2-hIgGFc transfected HEK293 cell lysates with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975).Flow Cytometry
Flow cytometric analysis of Ramos cells with PVRL2 monoclonal antibody, clone 4A11B12 (Cat # MAB17975) (Green). Red: Negative Control. -
Gene Info — PVRL2
Entrez GeneID
5819Protein Accession#
Q92692Gene Name
PVRL2
Gene Alias
CD112, HVEB, PRR2, PVRR2
Gene Description
poliovirus receptor-related 2 (herpesvirus entry mediator B)
Omim ID
600798Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
herpesvirus entry mediator B|herpesvirus entry protein B|nectin 2|poliovirus receptor related 2|poliovirus receptor-like 2
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Interactome
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Pathway
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Disease
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