CCR3 monoclonal antibody, clone 8E9H10
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CCR3-hIgGFc transfected HEK293 cell lysates with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962).
Flow Cytometry
Flow cytometric analysis of HL-60 cells with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant human CCR3.
Immunogen
Recombinant protein corresponding to human CCR3.
Host
Mouse
Theoretical MW (kDa)
41
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CCR3-hIgGFc transfected HEK293 cell lysates with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962).Flow Cytometry
Flow cytometric analysis of HL-60 cells with CCR3 monoclonal antibody, clone 8E9H10 (Cat # MAB17962) (Green). Red: Negative Control. -
Gene Info — CCR3
Entrez GeneID
1232Protein Accession#
P51677Gene Name
CCR3
Gene Alias
CC-CKR-3, CD193, CKR3, CMKBR3, MGC102841
Gene Description
chemokine (C-C motif) receptor 3
Omim ID
601268Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq
Other Designations
CC chemokine receptor 3|OTTHUMP00000164718|b-chemokine receptor|eosinophil CC chemokine receptor 3|eosinophil eotaxin receptor
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Interactome
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Pathway
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Disease
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