PRKAB2 monoclonal antibody, clone 7A8C3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PRKAB2-hIgGFc transfected HEK293 cell lysates with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940).
Flow Cytometry
Flow cytometric analysis of HeLa cells with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human PRKAB2.
Immunogen
Recombinant protein corresponding to amino acids 1-120 of human PRKAB2.
Host
Mouse
Theoretical MW (kDa)
30.3
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: PRKAB2-hIgGFc transfected HEK293 cell lysates with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940).Flow Cytometry
Flow cytometric analysis of HeLa cells with PRKAB2 monoclonal antibody, clone 7A8C3 (Cat # MAB17940) (Green). Red: Negative Control. -
Gene Info — PRKAB2
Entrez GeneID
5565Protein Accession#
O43741Gene Name
PRKAB2
Gene Alias
MGC61468
Gene Description
protein kinase, AMP-activated, beta 2 non-catalytic subunit
Omim ID
602741Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. [provided by RefSeq
Other Designations
5'-AMP-activated protein kinase, beta-2 subunit|AMP-activated protein kinase beta 2 non-catalytic subunit|AMPK beta 2|AMPK beta-2 chain|OTTHUMP00000015910
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Interactome
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Pathway
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Disease
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