GRIK3 monoclonal antibody, clone 2B3D1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human GRIK3.
Immunogen
Recombinant protein corresponding to amino acids 32-173 of human GRIK3.
Host
Mouse
Theoretical MW (kDa)
104
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Immunofluorescence (1:200-1:1000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: GRIK3-hIgGFc transfected HEK293 cell lysates with GRIK3 monoclonal antibody, clone 2B3D1 (Cat # MAB17935).Immunofluorescence
Immunofluorescent staining of HeLa cells with GRIK3 monoclonal antibody, clone 2B3D1 (Cat # MAB17935) (Green). Blue: DRAQ5 fluorescent DNA dye.Enzyme-linked Immunoabsorbent Assay
ELISA analysis with GRIK3 monoclonal antibody, clone 2B3D1 (Cat # MAB17935). -
Gene Info — GRIK3
Entrez GeneID
2899Protein Accession#
Q13003Gene Name
GRIK3
Gene Alias
EAA5, GLR7, GLUR7, GluR7a
Gene Description
glutamate receptor, ionotropic, kainate 3
Omim ID
138243Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq
Other Designations
OTTHUMP00000004360|dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7))|excitatory amino acid receptor 5|glutamate receptor 7
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