ATG4C monoclonal antibody, clone 2E10H7
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ATG4C.
Immunogen
Recombinant protein corresponding to amino acids 321-458 of human ATG4C.
Host
Mouse
Theoretical MW (kDa)
52.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: ATG4C-hIgGFc transfected HEK293 cell lysates with ATG4C monoclonal antibody, clone 2E10H7 (Cat # MAB17927).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with ATG4C monoclonal antibody, clone 2E10H7 (Cat # MAB17927). -
Gene Info — ATG4C
Entrez GeneID
84938Protein Accession#
Q96DT6Gene Name
ATG4C
Gene Alias
APG4-C, APG4C, AUTL1, AUTL3, FLJ14867
Gene Description
ATG4 autophagy related 4 homolog C (S. cerevisiae)
Omim ID
611339Gene Ontology
HyperlinkGene Summary
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq
Other Designations
APG4 autophagy 4 homolog C|AUT-like 1, cysteine endopeptidase|AUT-like 3 cysteine endopeptidase|OTTHUMP00000010715|autophagin-3|autophagy-related cysteine endopeptidase 3
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Interactome
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Pathway
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