GRM7 monoclonal antibody, clone 7G8D3
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: GRM7-hIgGFc transfected HEK293 cell lysates with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924).
Immunofluorescence
Immunofluorescent staining of HeLa cells with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924) (Green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924).
Flow Cytometry
Flow cytometric analysis of SH-SY5Y cells with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human GRM7.
Immunogen
Recombinant protein corresponding to amino acids 454-590 of human GRM7.
Host
Mouse
Theoretical MW (kDa)
102.3
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Immunofluorescence (1:200-1:1000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: GRM7-hIgGFc transfected HEK293 cell lysates with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924).Immunofluorescence
Immunofluorescent staining of HeLa cells with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924) (Green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.Enzyme-linked Immunoabsorbent Assay
ELISA analysis with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924).Flow Cytometry
Flow cytometric analysis of SH-SY5Y cells with GRM7 monoclonal antibody, clone 7G8D3 (Cat # MAB17924) (Green). Red: Negative Control. -
Gene Info — GRM7
Entrez GeneID
2917Protein Accession#
Q14831Gene Name
GRM7
Gene Alias
FLJ40498, GLUR7, GPRC1G, MGLUR7, mGlu7
Gene Description
glutamate receptor, metabotropic 7
Omim ID
604101Gene Ontology
HyperlinkGene Summary
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
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