BCL2L10 monoclonal antibody, clone 8A11G12
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BCL2L10-hIgGFc transfected HEK293 cell lysates with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918).
Flow Cytometry
Flow cytometric analysis of HeLa cells with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918) (Green). Red: Negative Control.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human BCL2L10.
Immunogen
Recombinant protein corresponding to amino acids 31-186 of human BCL2L10.
Host
Mouse
Theoretical MW (kDa)
22
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Flow Cytometry (1:200-1:400)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: BCL2L10-hIgGFc transfected HEK293 cell lysates with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918).Flow Cytometry
Flow cytometric analysis of HeLa cells with BCL2L10 monoclonal antibody, clone 8A11G12 (Cat # MAB17918) (Green). Red: Negative Control. -
Gene Info — BCL2L10
Entrez GeneID
10017Protein Accession#
Q9HD36Gene Name
BCL2L10
Gene Alias
BCL-B, Boo, Diva, MGC129810, MGC129811
Gene Description
BCL2-like 10 (apoptosis facilitator)
Omim ID
606910Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq
Other Designations
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Interactome
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Disease
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