ATL1 monoclonal antibody, clone 1F6B12
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human ATL1.
Immunogen
Recombinant protein corresponding to amino acids 1-100 of human ATL1.
Host
Mouse
Theoretical MW (kDa)
63.5
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: ATL1-hIgGFc transfected HEK293 cell lysates with ATL1 monoclonal antibody, clone 1F6B12 (Cat # MAB17914).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with ATL1 monoclonal antibody, clone 1F6B12 (Cat # MAB17914). -
Gene Info — ATL1
Entrez GeneID
51062Protein Accession#
Q8WXF7Gene Name
ATL1
Gene Alias
AD-FSP, FSP1, GBP3, SPG3, SPG3A, atlastin1
Gene Description
atlastin GTPase 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
GTP-binding protein 3|atlastin-1|brain-specific GTP-binding protein|guanine nucleotide-binding protein 3|guanylate-binding protein 3
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Interactome
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Disease
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