CDC37 monoclonal antibody, clone 6B3B5
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CDC37-hIgGFc transfected HEK293 cell lysates with CDC37 monoclonal antibody, clone 6B3B5 (Cat # MAB17887).
Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CDC37 monoclonal antibody, clone 6B3B5 (Cat # MAB17887).
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant human CDC37.
Immunogen
Recombinant protein corresponding to amino acids 241-378 of human CDC37.
Host
Mouse
Theoretical MW (kDa)
44.5
Reactivity
Human
Form
Liquid
Isotype
IgG2a
Recommend Usage
ELISA (1:10000)
Western Blot (1:100-1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.05% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of Lane 1: HEK293 and Lane 2: CDC37-hIgGFc transfected HEK293 cell lysates with CDC37 monoclonal antibody, clone 6B3B5 (Cat # MAB17887).Enzyme-linked Immunoabsorbent Assay
ELISA analysis with CDC37 monoclonal antibody, clone 6B3B5 (Cat # MAB17887). -
Gene Info — CDC37
Entrez GeneID
11140Protein Accession#
Q16543Gene Name
CDC37
Gene Alias
P50CDC37
Gene Description
cell division cycle 37 homolog (S. cerevisiae)
Omim ID
605065Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq
Other Designations
CDC37 (cell division cycle 37, S. cerevisiae, homolog)|CDC37 cell division cycle 37 homolog|Hsp90 co-chaperone Cdc37|cell division cycle 37 protein
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Interactome
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Disease
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